Saget was pronounced dead at the scene after he was found unresponsive at the Ritz Carlton in Orlando, Florida, according to the Orange County Sheriff’s Office.
The actor was best known for his role as Danny Tanner on the hit sitcom Full House, which ran on ABC from 1987 to 1995. The actor returned when the series was revived on Netflix in 2016, retitled Fuller House.
His family have issued a statement confirming the death of “our beloved Bob” and invited fans “to join us in remembering the love and laughter that Bob brought to the world”.
Marvel star Kat Dennings – who acted opposite Saget in the sitcom Raising Dad – was one of the first to pay tribute to the late actor on Twitter.
Dennings wrote: “Oh god. Bob Saget!!! The loveliest man. I was his TV daughter for one season and he was always so kind and protective. So so sorry for his family.”
John Stamos – who starred as Uncle Jesse on Full House – wrote that he was “broken” and “gutted” in response to the news.
“I am in complete and utter shock,” wrote Stamos on Twitter. “I will never ever have another friend like him. I love you so much Bobby.”
Candace Cameron Bure – who played Danny’s daughter DJ Tanner – also paid tribute to Saget on Twitter.
“I don’t know what to say. I have no words. Bob was one of the best humans beings I’ve ever known in my life. I loved him so much,” wrote Bure.
Talk show host Jon Stewart called Saget “the funniest and nicest”, while The Facts of Life star Norman Lear said that Saget was “as lovely as he was funny”.
Lear wrote: “We were close friends and I could not have loved him more.”
Steve Martin responded to the news of Saget’s death, calling it a “sad day for comedy world”.
“BOB… it was great to know you… Oh are you going to make God blush,” wrote Henry Winkler, referring to Saget’s non-family friendly jokes.
Fellow comedian Mike Young said that “my comedy will be my tribute”. The pair toured together for 10 years. Young added: “To work without you already hurts.”
Netflix CEO Ted Sarandos and former Walt Disney CEO Bob Iger also paid tribute to Saget on social media.
Andy Cohen praised Saget for being “so generous with his feelings” while Ben Stiller called the late actor “an incredibly kind and funny person”.
Comedian, director and producer Judd Apatow (previously The 40-Year-Old Virgin and Knocked Up) said that Saget was “there for everyone”, calling him “a beautiful soul”.
Billy Crystal, Chelsea Handler, Community’s Joel McHale, Ken Jeong, Kathy Griffin and The Office star BJ Novak were also among those to pay tribute to the comedian.
Saget is survived by his wife Kelly Rizzo and three children.